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Giving up smoking with or without treatment can cause a variety of symptoms. These include changes in mood (such as feeling depressed, irritable, frustrated or anxious), difficulty in sleeping or concentrating, reduced heart rate and improved appetite or weight gain.
Medicines and their likely side effects can influence individual people in dissimilar ways. The following are some of the side effects that are known to be related with using this medicine to help give up smoking. It is not known if these side effects are a result of using the medicine, or a result of giving up smoking. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

Very common (affect more than 1 in 10 people)
• Nausea.
• Headache.
• Difficulty sleeping (insomnia).
• Abnormal dreams.

Common (affect between 1 in 10 and 1 in 100 people)
• Sleepiness or fatigue.
• Dizziness.
• Change in taste.
• Dry mouth.
• Disturbances of the gut such as constipation, diarrhea, vomiting, abdominal discomfort or bloating, indigestion, wind (flatulence).
• Increased appetite.

Uncommon (affect between 1 in 100 and 1 in 1000 people)
• Decreased appetite.
• Inflammation of the nose and throat (nasopharyngitis), sinuses (sinusitis) or lungs (bronchitis).
• Feeling thirsty.
• Shortness of breath, cough or hoarseness.
• Throat irritation.
• Runny nose.
• Snoring.
• Mood swings.
• Abnormal thinking.
• Changes in sex drive.
• Tremor.

This medicine might make you feel dizzy or sleepy and so could damage your ability to carry out potentially risky tasks such as driving or operating machinery. You should stay away from driving or operating machinery until you know how this medicine have an effect on you and are sure that it won’t affect your ability to perform such activities carefully.

There have been reports of suicidal thoughts or behavior in people taking this medicine to aid them quit smoking. It is very difficult to know if this is due to the medicine, as giving up smoking itself can make people down in the dumps, particularly if they previously have a mental health problem, and hopelessness is associated with suicidal thoughts.

However, not all people experiencing depression and suicidal thoughts while taking this medicine had a previous history of psychiatric illness, or had stopped smoking. For this reason, if you start to feel agitated or disheartened, or experience any changes in your behavior or thoughts about suicide or harming yourself during treatment with this medicine, you should discontinue taking it and discuss with your doctor without delay.

Some people may stumble on that when they stop taking this medicine their urge to smoke returns. They may also feel short-tempered, disheartened or have difficulty sleeping. To stay away from this, your doctor may consider reducing your dose at a snail’s pace when you finish treatment with this medicine, to a certain extent than stopping it immediately. Discuss this with your doctor.