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Archive for November 24th, 2009

Champix (varenicline)

Tuesday, November 24th, 2009

Champix tablets contain the active ingredient varenicline, a drug used to help people who are addicted to nicotine quit smoking. It works in the brain, but not the same as nicotine replacement therapy.
Varenicline type of medicine called nicotinic acetylcholine receptor partial agonist. This means that operates on the same receptors in the brain as nicotine.
Varenicline works by stimulating nicotine receptors in the brain. This produces the effect that relieves the craving and withdrawal symptoms you get when you stop smoking.
At the same time, varenicline blocks nicotine from acting on nicotinic receptors. This prevents any nicotine inhaled in tobacco smoke to be useful and pleasant effect.
You should set a date when you stop smoking and start taking this medicine one-dvatýden advance. This is because the medicine needs time to start working.
The dose is increased gradually in the first week of treatment (as directed by your doctor or pharmacist), and the drug should then be twice daily for 12 weeks. If you have successfully quit smoking by the end of the 12th week, the physician may offer additional 12 weeks of treatment.
The tablets are swallowed whole with water. They can be taken with or without food.
You should seek help and support as much as possible while quit, even when taking this medicine because it will increase your chances of success. With your doctor, nurse or local pharmacist can give you all the help.
Warning:
• This medicine may make you feel dizzy or sleepy and so could impair your ability to perform hazardous tasks such as driving or operating machinery. You should avoid driving or operating machinery until you know how this medicine affects you and are sure that it does not affect your ability to perform such activities safely.
• There have been reports of suicidal thoughts or behavior in people taking this medication to help them stop smoking. It is very difficult to know whether this is due to medicine, who want to quit smoking itself can make people depressed, especially if they already have mental problems and depression associated with suicidal ideation. But not all people experience depression and suicidal thoughts when taking this medicine had a previous history of mental illness, or had stopped smoking. For this reason, if you start to feel anxious and depressed, or experience any changes in your behavior or thoughts of suicide or injure yourself during treatment with this medicine, stop taking it and contact your doctor immediately.
• some people might think that when they stop taking this medicine their urge to smoke yields. They may also feel irritable, depressed or have trouble sleeping. To avoid this, your doctor may consider reducing the dose slowly when you stop taking this medicine, rather than stopping it abruptly. Discuss this with your doctor.